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The EBI2 signalling pathway plays a role in cellular crosstalk between astrocytes and macrophages

EBI2 is a G protein-coupled receptor activated by oxysterol 7α, 25-dihydroxycholesterol (7α25HC) and regulates T cell-dependant antibody response and B cell migration. We recently found EBI2 is expressed in human astrocytes, regulates intracellular signalling and modulates astrocyte migration. Here,...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Rutkowska, Aleksandra, O’Sullivan, Sinead A., Christen, Isabelle, Zhang, Juan, Sailer, Andreas W., Dev, Kumlesh K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863252/
https://ncbi.nlm.nih.gov/pubmed/27166278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25520
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