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Identification of a specific inhibitor for DNA ligase I in human cells.

A protein inhibitor for human DNA ligase I has recently been identified. It was copurified with a fraction of the enzymes from HeLa cells through several steps of chromatography. The inhibitor was first identified by the absence of ligation activity of the associated enzyme, while it retained the ab...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Yang, S W, Becker, F F, Chan, J Y
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48630/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1549587/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.6.2227
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