The Viral Polymerase Inhibitor 7-Deaza-2’-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Model

Zika virus (ZIKV) is an emerging flavivirus typically causing a dengue-like febrile illness, but neurological complications, such as microcephaly in newborns, have potentially been linked to this viral infection. We established a panel of in vitro assays to allow the identification of ZIKV inhibitor...

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Detalles Bibliográficos
Publicado en:PLoS Negl Trop Dis
Main Authors: Zmurko, Joanna, Marques, Rafael E., Schols, Dominique, Verbeken, Erik, Kaptein, Suzanne J.F., Neyts, Johan
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862633/
https://ncbi.nlm.nih.gov/pubmed/27163257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004695
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