An Open, Randomized, Single-Center, Crossover Pharmacokinetic Study of Meropenem after Intraperitoneal and Intravenous Administration in Patients Receiving Automated Peritoneal Dialysis

The objective of this study was to determine the pharmacokinetic profile of meropenem in automated peritoneal dialysis (APD) patients. In 6 patients without peritonitis, a single dose of 0.5 g of meropenem was applied intraperitoneally (i.p.) or intravenously (i.v.) and concentrations in serum and d...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Wiesholzer, Martin, Pichler, Petra, Reznicek, Gottfried, Wimmer, Michaela, Kussmann, Manuel, Balcke, Peter, Burgmann, Heinz, Zeitlinger, Markus, Poeppl, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862547/
https://ncbi.nlm.nih.gov/pubmed/26902765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02664-15
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