An Open, Randomized, Single-Center, Crossover Pharmacokinetic Study of Meropenem after Intraperitoneal and Intravenous Administration in Patients Receiving Automated Peritoneal Dialysis

The objective of this study was to determine the pharmacokinetic profile of meropenem in automated peritoneal dialysis (APD) patients. In 6 patients without peritonitis, a single dose of 0.5 g of meropenem was applied intraperitoneally (i.p.) or intravenously (i.v.) and concentrations in serum and d...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Wiesholzer, Martin, Pichler, Petra, Reznicek, Gottfried, Wimmer, Michaela, Kussmann, Manuel, Balcke, Peter, Burgmann, Heinz, Zeitlinger, Markus, Poeppl, Wolfgang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
Materias:
Clinical Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862547/
https://ncbi.nlm.nih.gov/pubmed/26902765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02664-15
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