Sequential Treatment of Biofilms with Aztreonam and Tobramycin Is a Novel Strategy for Combating Pseudomonas aeruginosa Chronic Respiratory Infections

Traditional therapeutic strategies to control chronic colonization in cystic fibrosis (CF) patients are based on the use of a single nebulized antibiotic. In this study, we evaluated the therapeutic efficacy and dynamics of antibiotic resistance in Pseudomonas aeruginosa biofilms under sequential th...

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Библиографические подробности
Опубликовано в: :Antimicrob Agents Chemother
Главные авторы: Rojo-Molinero, Estrella, Macià, María D., Rubio, Rosa, Moyà, Bartolomé, Cabot, Gabriel, López-Causapé, Carla, Pérez, José L., Cantón, Rafael, Oliver, Antonio
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2016
Предметы:
Experimental Therapeutics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862541/
https://ncbi.nlm.nih.gov/pubmed/26926631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00196-16
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