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Novobiocin Susceptibility of MukBEF-Deficient Escherichia coli Is Combinatorial with Efflux and Resides in DNA Topoisomerases

Condensins play a key role in the global organization of bacterial chromosomes. In Escherichia coli, the inactivation of its sole condensin MukBEF induces severe growth defects and renders cells hypersusceptible to novobiocin. We report here that this hypersusceptibility can be observed in TolC-defi...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Petrushenko, Zoya M., Zhao, Hang, Zgurskaya, Helen I., Rybenkov, Valentin V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862531/
https://ncbi.nlm.nih.gov/pubmed/26926630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03102-15
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