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Distinct Pharmacodynamic Activity of Rilpivirine in Ectocervical and Colonic Explant Tissue
A long-acting injectable form of rilpivirine (RPV) is being evaluated in clinical trials for the prevention of HIV infection. Preclinical testing was undertaken to define RPV pharmacokinetic (PK) and pharmacodynamic (PD) activities in ectocervical and colonic tissue treated in vitro. Tenfold dilutio...
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| Publicado no: | Antimicrob Agents Chemother |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4862523/ https://ncbi.nlm.nih.gov/pubmed/26902757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00167-16 |
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