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Distinct Pharmacodynamic Activity of Rilpivirine in Ectocervical and Colonic Explant Tissue
A long-acting injectable form of rilpivirine (RPV) is being evaluated in clinical trials for the prevention of HIV infection. Preclinical testing was undertaken to define RPV pharmacokinetic (PK) and pharmacodynamic (PD) activities in ectocervical and colonic tissue treated in vitro. Tenfold dilutio...
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| Publié dans: | Antimicrob Agents Chemother |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4862523/ https://ncbi.nlm.nih.gov/pubmed/26902757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00167-16 |
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