Differential In Vitro and In Vivo Toxicities of Antimicrobial Peptide Prodrugs for Potential Use in Cystic Fibrosis

There has been considerable interest in the use of antimicrobial peptides (AMPs) as antimicrobial agents for the treatment of many conditions, including cystic fibrosis (CF). The challenging conditions of the CF patient lung require robust AMPs that are active in an environment of high proteolytic a...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Forde, Éanna, Schütte, André, Reeves, Emer, Greene, Catherine, Humphreys, Hilary, Mall, Marcus, Fitzgerald-Hughes, Deirdre, Devocelle, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862519/
https://ncbi.nlm.nih.gov/pubmed/26902766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00157-16
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