Acquisition of Broad-Spectrum Cephalosporin Resistance Leading to Colistin Resistance in Klebsiella pneumoniae

An extended-spectrum β-lactamase (ESBL)-producing and colistin-resistant Klebsiella pneumoniae clinical isolate was recovered from a patient who was treated with cefotaxime. This isolate harbored a bla(CTX-M-15) ESBL gene that was associated with an ISEcp1 insertion sequence. Transposition of that t...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Jayol, Aurélie, Nordmann, Patrice, Desroches, Marine, Decousser, Jean-Winoc, Poirel, Laurent
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862518/
https://ncbi.nlm.nih.gov/pubmed/26953194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00237-16
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