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Targeting Fibronectin To Disrupt In Vivo Candida albicans Biofilms

New drug targets are of great interest for the treatment of fungal biofilms, which are routinely resistant to antifungal therapies. We theorized that the interaction of Candida albicans with matricellular host proteins would provide a novel target. Here, we show that an inhibitory protein (FUD) targ...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Nett, Jeniel E., Cabezas-Olcoz, Jonathan, Marchillo, Karen, Mosher, Deane F., Andes, David R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862492/
https://ncbi.nlm.nih.gov/pubmed/26902759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03094-15
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