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Role of Fks1p and Matrix Glucan in Candida albicans Biofilm Resistance to an Echinocandin, Pyrimidine, and Polyene

Candida infections frequently involve drug-resistant biofilm growth on device surfaces. Glucan synthase gene FKS1 has been linked to triazole resistance in Candida biofilms. We tested the impact of FKS1 modulation on susceptibility to additional antifungal classes. Reduction of FKS1 expression rende...

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Detalhes bibliográficos
Main Authors: Nett, Jeniel E., Crawford, Kyler, Marchillo, Karen, Andes, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916329/
https://ncbi.nlm.nih.gov/pubmed/20516280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00227-10
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