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SHOX Haploinsufficiency as a Cause of Syndromic and Nonsyndromic Short Stature

SHOX in the short arm pseudoautosomal region (PAR1) of sex chromosomes is one of the major growth genes in humans. SHOX haploinsufficiency results in idiopathic short stature and Léri-Weill dyschondrosteosis and is associated with the short stature of patients with Turner syndrome. The SHOX protein...

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Detalhes bibliográficos
Publicado no:Mol Syndromol
Main Authors: Fukami, Maki, Seki, Atsuhito, Ogata, Tsutomu
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862394/
https://ncbi.nlm.nih.gov/pubmed/27194967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000444596
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