Comparison of Burrowing and Stimuli-Evoked Pain Behaviors as End-Points in Rat Models of Inflammatory Pain and Peripheral Neuropathic Pain

Establishment and validation of ethologically-relevant, non-evoked behavioral end-points as surrogate measures of spontaneous pain in rodent pain models has been proposed as a means to improve preclinical to clinical research translation in the pain field. Here, we compared the utility of burrowing...

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Veröffentlicht in:Front Behav Neurosci
Hauptverfasser: Muralidharan, Arjun, Kuo, Andy, Jacob, Meera, Lourdesamy, Jacintha S., Carvalho, Lara Melo Soares Pinho De, Nicholson, Janet R., Corradini, Laura, Smith, Maree T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862327/
https://ncbi.nlm.nih.gov/pubmed/27242458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2016.00088
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