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Comparison of Burrowing and Stimuli-Evoked Pain Behaviors as End-Points in Rat Models of Inflammatory Pain and Peripheral Neuropathic Pain

Establishment and validation of ethologically-relevant, non-evoked behavioral end-points as surrogate measures of spontaneous pain in rodent pain models has been proposed as a means to improve preclinical to clinical research translation in the pain field. Here, we compared the utility of burrowing...

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Detalhes bibliográficos
Publicado no:Front Behav Neurosci
Main Authors: Muralidharan, Arjun, Kuo, Andy, Jacob, Meera, Lourdesamy, Jacintha S., Carvalho, Lara Melo Soares Pinho De, Nicholson, Janet R., Corradini, Laura, Smith, Maree T.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862327/
https://ncbi.nlm.nih.gov/pubmed/27242458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2016.00088
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