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Myo-inositol changes precede amyloid pathology and relate to APOE genotype in Alzheimer disease
OBJECTIVE: We aimed to test whether in vivo levels of magnetic resonance spectroscopy (MRS) metabolites myo-inositol (mI), N-acetylaspartate (NAA), and choline are abnormal already during preclinical Alzheimer disease (AD), relating these changes to amyloid or tau pathology, and functional connectiv...
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| Veröffentlicht in: | Neurology |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Lippincott Williams & Wilkins
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4862247/ https://ncbi.nlm.nih.gov/pubmed/27164711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000002672 |
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