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Effect of continued treatment with pirfenidone following clinically meaningful declines in forced vital capacity: analysis of data from three phase 3 trials in patients with idiopathic pulmonary fibrosis

BACKGROUND: The assessment of treatment response in idiopathic pulmonary fibrosis (IPF) is complicated by the variable clinical course. We examined the variability in the rate of disease progression and evaluated the effect of continued treatment with pirfenidone in patients who experienced meaningf...

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Détails bibliographiques
Publié dans:Thorax
Auteurs principaux: Nathan, Steven D, Albera, Carlo, Bradford, Williamson Z, Costabel, Ulrich, du Bois, Roland M, Fagan, Elizabeth A, Fishman, Robert S, Glaspole, Ian, Glassberg, Marilyn K, Glasscock, Kenneth F, King, Talmadge E, Lancaster, Lisa, Lederer, David J, Lin, Zhengning, Pereira, Carlos A, Swigris, Jeffrey J, Valeyre, Dominique, Noble, Paul W, Wells, Athol U
Format: Artigo
Langue:Inglês
Publié: BMJ Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862066/
https://ncbi.nlm.nih.gov/pubmed/26968970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2015-207011
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