Sensitivity Analyses of the Change in FVC in a Phase 3 Trial of Pirfenidone for Idiopathic Pulmonary Fibrosis

BACKGROUND: FVC outcomes in clinical trials on idiopathic pulmonary fibrosis (IPF) can be substantially influenced by the analytic methodology and the handling of missing data. We conducted a series of sensitivity analyses to assess the robustness of the statistical finding and the stability of the...

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Detalhes bibliográficos
Publicado no:Chest
Main Authors: Lederer, David J., Bradford, Williamson Z., Fagan, Elizabeth A., Glaspole, Ian, Glassberg, Marilyn K., Glasscock, Kenneth F., Kardatzke, David, King, Talmadge E., Lancaster, Lisa H., Nathan, Steven D., Pereira, Carlos A., Sahn, Steven A., Swigris, Jeffrey J., Noble, Paul W.
Formato: Artigo
Idioma:Inglês
Publicado em: American College of Chest Physicians 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493875/
https://ncbi.nlm.nih.gov/pubmed/25856121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1378/chest.14-2817
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