Finding a new therapeutic approach for no-option Parkinsonisms: mesenchymal stromal cells for progressive supranuclear palsy

BACKGROUND: The trophic, anti-apoptotic and regenerative effects of bone marrow mesenchymal stromal cells (MSC) may reduce neuronal cell loss in neurodegenerative disorders. METHODS: We used MSC as a novel candidate therapeutic tool in a pilot phase-I study for patients affected by progressive supra...

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Veröffentlicht in:J Transl Med
Hauptverfasser: Canesi, Margherita, Giordano, Rosaria, Lazzari, Lorenza, Isalberti, Maurizio, Isaias, Ioannis Ugo, Benti, Riccardo, Rampini, Paolo, Marotta, Giorgio, Colombo, Aurora, Cereda, Emanuele, Dipaola, Mariangela, Montemurro, Tiziana, Viganò, Mariele, Budelli, Silvia, Montelatici, Elisa, Lavazza, Cristiana, Cortelezzi, Agostino, Pezzoli, Gianni
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862050/
https://ncbi.nlm.nih.gov/pubmed/27160012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0880-2
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