Microtubule defects in mesenchymal stromal cells distinguish patients with Progressive Supranuclear Palsy

Progressive Supranuclear Palsy (PSP) is a rare neurodegenerative disease whose etiopathogenesis remains elusive. The intraneuronal accumulation of hyperphosphorylated Tau, a pivotal protein in regulating microtubules (MT), leads to include PSP into tauopathies. Pathological hallmarks are well known...

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Vydáno v:J Cell Mol Med
Hlavní autoři: Calogero, Alessandra Maria, Viganò, Mariele, Budelli, Silvia, Galimberti, Daniela, Fenoglio, Chiara, Cartelli, Daniele, Lazzari, Lorenza, Lehenkari, Petri, Canesi, Margherita, Giordano, Rosaria, Cappelletti, Graziella, Pezzoli, Gianni
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908108/
https://ncbi.nlm.nih.gov/pubmed/29502334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13545
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