Stopping guidelines for an effectiveness trial: what should the protocol specify?

BACKGROUND: Despite long-standing problems in decisions to stop clinical trials, stopping guidelines are often vague or unspecified in the trial protocol. Clear, well-conceived guidelines are especially important to assist the data monitoring committees for effectiveness trials. MAIN TEXT: To specif...

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Publicat a:Trials
Autors principals: Tyson, Jon E., Pedroza, Claudia, Wallace, Dennis, D’Angio, Carl, Bell, Edward F., Das, Abhik
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Commentary
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862046/
https://ncbi.nlm.nih.gov/pubmed/27165260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-016-1367-4
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