Stopping guidelines for an effectiveness trial: what should the protocol specify?

BACKGROUND: Despite long-standing problems in decisions to stop clinical trials, stopping guidelines are often vague or unspecified in the trial protocol. Clear, well-conceived guidelines are especially important to assist the data monitoring committees for effectiveness trials. MAIN TEXT: To specif...

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Bibliografiske detaljer
Udgivet i:Trials
Main Authors: Tyson, Jon E., Pedroza, Claudia, Wallace, Dennis, D’Angio, Carl, Bell, Edward F., Das, Abhik
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Commentary
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862046/
https://ncbi.nlm.nih.gov/pubmed/27165260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-016-1367-4
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