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Synthesis of a highly water-soluble acacetin prodrug for treating experimental atrial fibrillation in beagle dogs
We previously reported that duodenal administration of the natural flavone acacetin can effectively prevent the induction of experimental atrial fibrillation (AF) in canines; however, it may not be used intravenously to terminate AF due to its poor water-solubility. The present study was to design a...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4861903/ https://ncbi.nlm.nih.gov/pubmed/27160397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25743 |
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