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Mesenchymal Stem Cells Attenuate NADPH Oxidase-Dependent High Mobility Group Box 1 Production and Inhibit Abdominal Aortic Aneurysms
OBJECTIVE: Abdominal aortic aneurysm (AAA) formation is characterized by inflammation, smooth muscle activation and matrix degradation. This study tests the hypothesis that macrophage-produced high mobility group box1 (HMGB1) production is dependent on NADPH oxidase (Nox2) which leads to increase in...
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| Udgivet i: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4861899/ https://ncbi.nlm.nih.gov/pubmed/26988591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307373 |
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