Myocardial Galectin-3 Expression Is Associated with Remodeling of the Pressure-Overloaded Heart and May Delay the Hypertrophic Response without Affecting Survival, Dysfunction, and Cardiac Fibrosis

The β-galactoside–binding animal lectin galectin-3 is predominantly expressed by activated macrophages and is a promising biomarker for patients with heart failure. Galectin-3 regulates inflammatory and fibrotic responses; however, its role in cardiac remodeling remains unclear. We hypothesized that...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Pathol
Prif Awduron: Frunza, Olga, Russo, Ilaria, Saxena, Amit, Shinde, Arti V., Humeres, Claudio, Hanif, Waqas, Rai, Vikrant, Su, Ya, Frangogiannis, Nikolaos G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Investigative Pathology 2016
Pynciau:
Regular Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861760/
https://ncbi.nlm.nih.gov/pubmed/26948424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.12.017
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