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A computational model of cardiac fibroblast signaling predicts context-dependent drivers of myofibroblast differentiation

Cardiac fibroblasts support heart function, and aberrant fibroblast signaling can lead to fibrosis and cardiac dysfunction. Yet how signaling molecules drive myofibroblast differentiation and fibrosis in the complex signaling environment of cardiac injury remains unclear. We developed a large-scale...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Mol Cell Cardiol
Egile Nagusiak: Zeigler, A.C., Richardson, W. J., Holmes, J. W., Saucerman, J. J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861657/
https://ncbi.nlm.nih.gov/pubmed/27017945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.03.008
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