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Subunit-selective N-Methyl-d-aspartate (NMDA) Receptor Signaling through Brefeldin A-resistant Arf Guanine Nucleotide Exchange Factors BRAG1 and BRAG2 during Synapse Maturation

The maturation of glutamatergic synapses in the CNS is regulated by NMDA receptors (NMDARs) that gradually change from a GluN2B- to a GluN2A-dominated subunit composition during postnatal development. Here we show that NMDARs control the activity of the small GTPase ADP-ribosylation factor 6 (Arf6)...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Elagabani, Mohammad Nael, Briševac, Dušica, Kintscher, Michael, Pohle, Jörg, Köhr, Georg, Schmitz, Dietmar, Kornau, Hans-Christian
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861478/
https://ncbi.nlm.nih.gov/pubmed/26884337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.691717
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