Recruitment of RNA polymerase II by the pioneer transcription factor PHA-4

Pioneer transcription factors initiate cell-fate changes by binding to silent target genes. They are among the first factors to bind key regulatory sites and facilitate chromatin opening. Here, we identify an additional role for pioneer factors. In early Caenorhabditis elegans foregut development, t...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Science
Auteurs principaux: Hsu, H.-T., Chen, H.-M., Yang, Z., Wang, J., Lee, N. K., Burger, A., Zaret, K., Liu, T., Levine, E., Mango, S. E.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861314/
https://ncbi.nlm.nih.gov/pubmed/26089518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab1223
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires