Wordt geladen...
A RASSF1A polymorphism restricts p53/p73 activation and associates with poor survival and accelerated age of onset of soft tissue sarcoma
RASSF1A (Ras association domain containing family 1A), a tumor suppressor gene that is frequently inactivated in human cancers, is phosphorylated by Ataxia Telangiectasia Mutated (ATM) on Ser131 upon DNA damage, leading to activation of a p73-dependent apoptotic response. A single nucleotide polymor...
Bewaard in:
| Gepubliceerd in: | Cancer Res |
|---|---|
| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2012
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4861210/ https://ncbi.nlm.nih.gov/pubmed/22389451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2906 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|