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The Effects of Chemotherapeutic Agents, Bleomycin, Etoposide, and Cisplatin, on Chromatin Remodeling in Male Rat Germ Cells

The coadministration of bleomycin, etoposide, and cisplatin (BEP) has increased the survival rate of testicular cancer patients to over 90%. Previous studies have demonstrated that BEP induces germ cell damage during the final stages of spermatogenesis, when major chromatin remodeling occurs. Chroma...

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Bibliografiske detaljer
Udgivet i:Biol Reprod
Main Authors: Bagheri-Sereshki, Negar, Hales, Barbara F., Robaire, Bernard
Format: Artigo
Sprog:Inglês
Udgivet: Society for the Study of Reproduction, Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861167/
https://ncbi.nlm.nih.gov/pubmed/26911428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.115.137802
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