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The Effects of Chemotherapeutic Agents, Bleomycin, Etoposide, and Cisplatin, on Chromatin Remodeling in Male Rat Germ Cells

The coadministration of bleomycin, etoposide, and cisplatin (BEP) has increased the survival rate of testicular cancer patients to over 90%. Previous studies have demonstrated that BEP induces germ cell damage during the final stages of spermatogenesis, when major chromatin remodeling occurs. Chroma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biol Reprod
Hauptverfasser: Bagheri-Sereshki, Negar, Hales, Barbara F., Robaire, Bernard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for the Study of Reproduction, Inc. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861167/
https://ncbi.nlm.nih.gov/pubmed/26911428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.115.137802
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