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The Effects of Chemotherapeutic Agents, Bleomycin, Etoposide, and Cisplatin, on Chromatin Remodeling in Male Rat Germ Cells

The coadministration of bleomycin, etoposide, and cisplatin (BEP) has increased the survival rate of testicular cancer patients to over 90%. Previous studies have demonstrated that BEP induces germ cell damage during the final stages of spermatogenesis, when major chromatin remodeling occurs. Chroma...

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Vydáno v:Biol Reprod
Hlavní autoři: Bagheri-Sereshki, Negar, Hales, Barbara F., Robaire, Bernard
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for the Study of Reproduction, Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861167/
https://ncbi.nlm.nih.gov/pubmed/26911428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.115.137802
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