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Temporal activation of XRCC1-mediated DNA repair is essential for muscle differentiation

Transient DNA strand break formation has been identified as an effective means to enhance gene expression in living cells. In the muscle lineage, cell differentiation is contingent upon the induction of caspase-mediated DNA strand breaks, which act to establish the terminal gene expression program....

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Detalles Bibliográficos
Publicado en:Cell Discov
Main Authors: Al-Khalaf, Mohammad H, Blake, Leanne E, Larsen, Brian D, Bell, Ryan A, Brunette, Steve, Parks, Robin J, Rudnicki, Michael A, McKinnon, Peter J, Jeffrey Dilworth, F, Megeney, Lynn A
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860966/
https://ncbi.nlm.nih.gov/pubmed/27462438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2015.41
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