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SMG7 is a critical regulator of p53 stability and function in DNA damage stress response

The p53 tumor suppressor functions as a transcription factor and plays a pivotal role in regulation of cellular response to DNA damage by activating various genes including those involved in cell cycle arrest. p53 stability is essential for its function during stress response; however, the molecular...

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Bibliografiska uppgifter
I publikationen:Cell Discov
Huvudupphovsmän: Luo, Hongwei, Cowen, Lauren, Yu, Guowu, Jiang, Wenguo, Tang, Yi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860962/
https://ncbi.nlm.nih.gov/pubmed/27462439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2015.42
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