Modulation of tumorigenesis by the pro-inflammatory microRNA miR-301a in mouse models of lung cancer and colorectal cancer

Lung cancer and colorectal cancer account for over one-third of all cancer deaths in the United States. MicroRNA-301a (miR-301a) is an activator of both nuclear factor-κB (NF-κB) and Stat3, and is overexpressed in both deadly malignancies. In this work, we show that genetic ablation of miR-301a redu...

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Pubblicato in:Cell Discov
Autori principali: Ma, Xiaodong, Yan, Fang, Deng, Qipan, Li, Fenge, Lu, Zhongxin, Liu, Mofang, Wang, Lisheng, Conklin, Daniel J, McCracken, James, Srivastava, Sanjay, Bhatnagar, Aruni, Li, Yong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860842/
https://ncbi.nlm.nih.gov/pubmed/27462406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2015.5
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