miR-301a as an NF-κB activator in pancreatic cancer cells

NF-κB is constitutively activated in most human pancreatic adenocarcinoma, which is a deadly malignancy with a 5-year survival rate of about 5%. In this work, we investigate whether microRNAs (miRNAs) contribute to NF-κB activation in pancreatic cancer. We demonstrate that miR-301a down-regulates NF...

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Bibliografiske detaljer
Main Authors: Lu, Zhongxin, Li, Yan, Takwi, Apana, Li, Benhui, Zhang, Jingwen, Conklin, Daniel J, Young, Ken H, Martin, Robert, Li, Yong
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020116/
https://ncbi.nlm.nih.gov/pubmed/21113131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.296
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