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Structural basis for Sfm1 functioning as a protein arginine methyltransferase

SPOUT proteins constitute one class of methyltransferases, which so far are found to exert activity mainly towards RNAs. Previously, yeast Sfm1 was predicted to contain a SPOUT domain but can methylate ribosomal protein S3. Here we report the crystal structure of Sfm1, which comprises of a typical S...

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Detalhes bibliográficos
Publicado no:Cell Discov
Main Authors: Lv, Fengjuan, Zhang, Tianlong, Zhou, Zhen, Gao, Shuaixin, Wong, Catherine CL, Zhou, Jin-Qiu, Ding, Jianping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860837/
https://ncbi.nlm.nih.gov/pubmed/27462434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2015.37
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