Immunogenicity and functional evaluation of iPSC-derived organs for transplantation

Whether physiologically induced pluripotent stem cell (iPSC)-derived organs are immunogenic and can be used for transplantation is unclear. Here, we generated iPSC-derived skin, islet, and heart representing three germ layers of the body through 4n complementation and evaluated their immunogenicity...

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Detalhes bibliográficos
Publicado no:Cell Discov
Main Authors: Wang, Libin, Cao, Jiani, Wang, Yukai, Lan, Tianshu, Liu, Lei, Wang, Weixu, Jin, Ning, Gong, Jiaqi, Zhang, Chao, Teng, Fei, Yan, Guoliang, Li, Chun, Li, Jiali, Wan, Haifeng, Hu, Baoyang, Li, Wei, Zhao, Xiaoyang, Qi, Zhongquan, Zhao, Tongbiao, Zhou, Qi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860825/
https://ncbi.nlm.nih.gov/pubmed/27462414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2015.15
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