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The redox protein p66(shc) mediates cochlear vascular dysfunction and transient noise-induced hearing loss
p66(shc), a member of the ShcA protein family, is essential for cellular response to oxidative stress, and elicits the formation of mitochondrial Reactive Oxygen Species (ROS), thus promoting vasomotor dysfunction and inflammation. Accordingly, mice lacking the p66 isoform display increased resistan...
Uloženo v:
| Vydáno v: | Sci Rep |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4860599/ https://ncbi.nlm.nih.gov/pubmed/27157635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25450 |
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