Riociguat (BAY 63-2521) and aspirin: a randomized, pharmacodynamic, and pharmacokinetic interaction study

Abstract. In preclinical studies, drugs that increase cyclic guanosine monophosphate levels have been shown to influence platelet function/aggregation; however, the effect of riociguat on human platelets is unclear. Aspirin, a platelet inhibitor, is likely to be given concomitantly in patients recei...

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Bibliographic Details
Published in:Pulm Circ
Main Authors: Frey, Reiner, Reber, Michael, Krätzschmar, Jörn, Unger, Sigrun, Mück, Wolfgang, Wensing, Georg
Format: Artigo
Language:Inglês
Published: University of Chicago Press 2016
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860533/
https://ncbi.nlm.nih.gov/pubmed/27162625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/685014
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