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Motor Alterations Induced by Chronic 4-Aminopyridine Infusion in the Spinal Cord In vivo: Role of Glutamate and GABA Receptors

Motor neuron (MN) degeneration is the pathological hallmark of MN diseases, a group of neurodegenerative disorders clinically manifested as muscle fasciculations and hyperreflexia, followed by paralysis, respiratory failure, and death. Ample evidence supports a role of glutamate-mediated excitotoxic...

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Détails bibliographiques
Publié dans:Front Neurosci
Auteurs principaux: Lazo-Gómez, Rafael, Tapia, Ricardo
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860413/
https://ncbi.nlm.nih.gov/pubmed/27242406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00200
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