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NBQX, a highly selective competitive antagonist of AMPA and KA ionotropic glutamate receptors, increases seizures and mortality following picornavirus infection

Seizures occur due to an imbalance between excitation and inhibition, with the balance tipping towards excitation, and glutamate is the predominant excitatory neurotransmitter in the central nervous system of mammals. Since upregulation of expression and/or function of glutamate receptors can contri...

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書目詳細資料
發表在:Exp Neurol
Main Authors: Libbey, Jane E., Hanak, Tyler J., Doty, Daniel J., Wilcox, Karen S., Fujinami, Robert S.
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860063/
https://ncbi.nlm.nih.gov/pubmed/27072529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2016.04.010
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