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Type I Interferons Regulate the Magnitude and Functionality of Mouse Polyomavirus-Specific CD8 T Cells in a Virus Strain-Dependent Manner

Mouse polyomavirus (MPyV) is a ubiquitous persistent natural mouse pathogen. A glutamic acid (E)-to-glycine (G) difference at position 91 of the VP1 capsid protein shifts the profile of tumors induced by MPyV from an epithelial to a mesenchymal cell origin. Here we asked if this tropism difference a...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Qin, Qingsong, Shwetank, Frost, Elizabeth L., Maru, Saumya, Lukacher, Aron E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859723/
https://ncbi.nlm.nih.gov/pubmed/26984726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00199-16
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