The Inositol-3-Phosphate Synthase Biosynthetic Enzyme Has Distinct Catalytic and Metabolic Roles

Inositol levels, maintained by the biosynthetic enzyme inositol-3-phosphate synthase (Ino1), are altered in a range of disorders, including bipolar disorder and Alzheimer's disease. To date, most inositol studies have focused on the molecular and cellular effects of inositol depletion without c...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Frej, Anna D., Clark, Jonathan, Le Roy, Caroline I., Lilla, Sergio, Thomason, Peter A., Otto, Grant P., Churchill, Grant, Insall, Robert H., Claus, Sandrine P., Hawkins, Phillip, Stephens, Len, Williams, Robin S. B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859692/
https://ncbi.nlm.nih.gov/pubmed/26951199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00039-16
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