The Inositol-3-Phosphate Synthase Biosynthetic Enzyme Has Distinct Catalytic and Metabolic Roles

Inositol levels, maintained by the biosynthetic enzyme inositol-3-phosphate synthase (Ino1), are altered in a range of disorders, including bipolar disorder and Alzheimer's disease. To date, most inositol studies have focused on the molecular and cellular effects of inositol depletion without c...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Frej, Anna D., Clark, Jonathan, Le Roy, Caroline I., Lilla, Sergio, Thomason, Peter A., Otto, Grant P., Churchill, Grant, Insall, Robert H., Claus, Sandrine P., Hawkins, Phillip, Stephens, Len, Williams, Robin S. B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859692/
https://ncbi.nlm.nih.gov/pubmed/26951199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00039-16
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