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Myocardin-Related Transcription Factor A Activation by Competition with WH2 Domain Proteins for Actin Binding
The myocardin-related transcription factors (MRTFs) are coactivators of serum response factor (SRF)-mediated gene expression. Activation of MRTF-A occurs in response to alterations in actin dynamics and critically requires the dissociation of repressive G-actin–MRTF-A complexes. However, the mechani...
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| Publicado en: | Mol Cell Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4859682/ https://ncbi.nlm.nih.gov/pubmed/26976641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01097-15 |
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