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Myocardin-Related Transcription Factor A Activation by Competition with WH2 Domain Proteins for Actin Binding

The myocardin-related transcription factors (MRTFs) are coactivators of serum response factor (SRF)-mediated gene expression. Activation of MRTF-A occurs in response to alterations in actin dynamics and critically requires the dissociation of repressive G-actin–MRTF-A complexes. However, the mechani...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Biol
Prif Awduron: Weissbach, Julia, Schikora, Franziska, Weber, Anja, Kessels, Michael, Posern, Guido
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859682/
https://ncbi.nlm.nih.gov/pubmed/26976641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01097-15
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