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Investigations of the CLOCK and BMAL1 Proteins Binding to DNA: A Molecular Dynamics Simulation Study

The circadian locomotor output cycles kaput (CLOCK), and brain and muscle ARNT-like 1 (BMAL1) proteins are important transcriptional factors of the endogenous circadian clock. The CLOCK and BMAL1 proteins can regulate the transcription-translation activities of the clock-related genes through the DN...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Xue, Tuo, Song, Chunnian, Wang, Qing, Wang, Yan, Chen, Guangju
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859532/
https://ncbi.nlm.nih.gov/pubmed/27153104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155105
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