EGFR Interacts with the Fusion Protein of Respiratory Syncytial Virus Strain 2-20 and Mediates Infection and Mucin Expression

Respiratory syncytial virus (RSV) is the major cause of viral lower respiratory tract illness in children. In contrast to the RSV prototypic strain A2, clinical isolate RSV 2–20 induces airway mucin expression in mice, a clinically relevant phenotype dependent on the fusion (F) protein of the RSV st...

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Vydáno v:PLoS Pathog
Hlavní autoři: Currier, Michael G., Lee, Sujin, Stobart, Christopher C., Hotard, Anne L., Villenave, Remi, Meng, Jia, Pretto, Carla D., Shields, Michael D., Nguyen, Minh Trang, Todd, Sean O., Chi, Michael H., Hammonds, Jason, Krumm, Stefanie A., Spearman, Paul, Plemper, Richard K., Sakamoto, Kaori, Peebles, R. Stokes, Power, Ultan F., Moore, Martin L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859522/
https://ncbi.nlm.nih.gov/pubmed/27152417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005622
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