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Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway.

The mesolimbic dopaminergic system has been implicated in mediating the motivational effects of opioids and other drugs of abuse. The site of action of opioids within this system and the role of endogenous opioid peptides in modulating dopamine activity therein remain unknown. Employing the techniqu...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Spanagel, R, Herz, A, Shippenberg, T S
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1992
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48593/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1347943/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.6.2046
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